The cylindrocyclophane metabolic network. Each circle represents a unique feature from the LCMS data, and the circle area is proportional to the m/z value (z = 1 for all features). Solid lines represent feature similarity with a cosine score of at least 0.60 and at least four matching fragments or neutral losses in MS/MS spectra. Colours represent the fold change of the feature as shown in c. The two features in grey, connected to the network by dashed lines, represent artefacts from the automated MS/MS procedure that were not identified as real features in c.
