Line Plot from Scientific Research

Quantification of experiments from n = 11 neurosurgical donors (each a biological replicate) shows that the phagocytosis index normalized to the final value for the control condition for each experiment increases over time and that AD synapses are phagocytosed more and faster than control synapses (ANOVA after linear mixed effects model on square root transformed data with synaptoneurosome donor disease status, incubation time, neurosurgical brain region, microglial donor gender, and microglial donor age as fixed effects and donor as a random effect, effect of disease status of synapse donor F[1,396.09] = 122.74, p < 2 × 10−16, effect of incubation time F[24,396.25] = 119.49, p < 2 × 10−16).

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