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KASUMI-1 cells were transduced with dCas9-KRAB and sgRNAs (non-targeting [hNT] or human CDC20-targeting [hCDC20] gRNA-1/2/3). Cell viability assays were performed after 72 h of culture with DAC at the indicated concentrations. n = 2 for each group. Y axis values represent the relative therapeutic effect of adding concomitant drugs in percentiles.
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