Illustration from Scientific Research

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Organization of the Igh locus into sub-TADS (pink and blue circles) while a dynamic continuum of interaction occurs between the 3' sub-TAD and the VH region enabling diverse VH-to-DH recombination events (red dotted arrows). The peripheral regions of the Igh locus participate in interchromosomal interactions, for example with Ebf1 and Foxo1.
#Illustration#Pathway#Igh Locus#Sub-TADS#VH Region#VH-to-DH recombination#Interchromosomal Interactions#Ebf1#Foxo1
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