Workflow from Scientific Research

Open access visualization of Workflow, Illustration, Bar Plot, IP-MS, PLA
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Schematic overview of the workflows used for IP-MS and PLA. Tau complexes were immunoprecipitated from hiPSC-derived neurons and analyzed via HRM mass spectrometry (MS). Members of cytoplasmic ribonucleoprotein (RNP) complexes were identified as Tau-associated proteins. Their interactions with Tau were further examined in the brains of human patients with or without AD using PLA.

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