Microscopy from Scientific Research

(Left) Brightfield image of a day-8 blastoid 1 day after attachment to the 3D ECM via its polar TE. Note that the mural TE is in the distance, out of the focal plane of the ICM and polar TE. (Center) Brightfield image of a day-10 blastoid following attachment and collapse of the TE upon 3D ECM. (Right) Brightfield image of a blastoid maintained on 3D ECM until day 14. Day-14 blastoids feature complex post-implantation trophoblast structures, including invasive PVL and early SVL structures. Scale bar, 200 μm.

DOI