Protein Structure from Scientific Research

A view of the disulfide bond formed between C615 and C634, connecting two regions in the HELICc domain of DDM1. The molecular structure is shown as ribbons; cryo-EM density is shown as a gray volume. The first mutation of ddm1 to be isolated, ddm1-1, substitutes C615 for Y and has a strong DNA methylation defect.

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