Scatter Plot from Scientific Research

Average values of n / c YAP ratio of MCF10A cells seeded on laminin-coated PAA gels of different rigidities on treatment with different integrin-blocking antibodies ( n = 90/61/28/30/33, 104/72/38/58/26, 101/73/49/43/35, 121/70/40/69/38, 94/51/39/51/32, 105/62/51/46/34 of control or β4-/α6-/α3-/β1-antibodies-treated cells for substrates of increasing rigidity; mean of at least three independent experiments). The effect of both integrin blocking and substrate stiffness is significant ( P < 0.0001, two-way ANOVA).

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