Individual plasma HIV-1 RNA levels are shown in the four randomization groups during 25 weeks of ATI: c, placebo/bNAb (n = 11). Solid green arrows indicate lefitolimod injections. Solid red and blue triangles indicate 3BNC117 and 10-1074 infusions, respectively. Empty green arrows as well as red and blue triangles indicate placebo injections or infusions, respectively. Light gray shaded areas indicate time on ART, and white shaded areas indicate still interrupting ART during the 25 weeks of ATI. The three horizontal dotted lines indicates plasma HIV-1 RNA limit of quantification and 1,000 and 100,000 copies per milliliter, respectively. Viral rebound was defined as 4 weeks with plasma HIV-RNA >1,000 copies per milliliter or two consecutive measurements >100,000 copies per milliliter.
