The capillary blood glucose of a patient with T2D during the treatment period. (I) Illustration of the seven-point glucose profile during the first and last 24 h of the treatment period. Statistical significance was determined by two-sided paired t-test: pre-breakfast *** P < 0.001; post-breakfast, pre-lunch, post-lunch, post-dinner and pre-bedtime ** P < 0.05; pre-dinner * P < 0.10. (II) Mean daily capillary blood glucose. (III) Mean preprandial capillary blood glucose. (IV) Mean postprandial capillary blood glucose during the treatment period. The preprandial blood glucose target was 5.6–7.8 mmol L -1 ; the postprandial capillary blood glucose target was <10.0 mmol L -1 . (II–IV) Line, median; error bar, interquartile; n = 16 patients.