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Baseline characteristics of eight patients with progressive DMG H3K27M + before initiation of treatment with H3K27M-vac. Age specified in years, tumor size measured as product of maximal orthogonal diameter on contrast-enhanced T1-weighted MRI sequences (mm 2 ); cumulative dose of intensity-modulated radiotherapy measured in Gy; TMZ, temozolomide (75 mg m -2 body surface area (BSA)) daily during radiotherapy; CCNU, lomustine (110 mg m -2 BSA d1, TMZ mg m -2 BSA d2-6, q42d for six cycles); oral dexamethasone intake in mg d -1 . Brain illustration taken from Adobe Stock Standard under License ID 222738500.
#Heatmap#Patients#DMG H3K27M#H3K27M-vac#Tumor size#MRI#Radiotherapy#Temozolomide#Lomustine#Dexamethasone
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