Scatter Plot from Scientific Research

Cumulative distribution function of subclonal mutation evolution M ( f ), as described in Williams et al. 44 , for Msh2 KO colon tumors. M ( f )= μ / β (1/ f – 1/ f max ), where f is the VAF/purity, μ the rate of somatic mutations and β the fraction of cell divisions where both lineages survive. Linear distribution of 1/ f (red line) is consistent with a neutral model of evolution.

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