Scatter Plot from Scientific Research

Directionality consistency-based haQTL tissue-sharing analysis. Lower, between-tissue directionality consistency ( y axis on the right) of the lead haQTL effect size ( y axis on the left) increases as the P value significance of the haQTLs in the replication tissue ( x axis) increases, separated by positive effect (right half-plane) and negative effect (left half-plane) of the matched haQTL–ARE pair in the discovery tissue; the examples 1–3 (shared ARE between tissues) from a are labeled. Upper, density of lead haQTLs in each of the nominal P value bins; the proportion and the corresponding consistency rates of each group are shown in parentheses in the figure legend.

DOI