Violin plots showing p53 pathway gene score per cells with each genetic variant. * P < 0.03; NS, not significant; two-sided t-test. P = 1.7 x 10 -33, 3.7 x 10 -29, 1.3 x 10 -6, 2.1 x 10 -14, 1.5 x 10 -6, 3.8 x 10 -7, 2.1 x 10 -2, 9.5 x 10 -9, 7.8 x 10 -5, 2.6 x 10 -7, 7.2 x 10 -27, 6.9 x 10 -4, 3.9 x 10 -7, 1.5 x 10 -88, 2.8 x 10 -6, 2.0 x 10 -30, 8.7 x 10 -23, 5.0 x 10 -67, 1.4 x 10 -9, 4.4 x 10 -14, 5.7 x 10 -14, 3.3 x 10 -37, 3.0 x 10 -13, 5.8 x 10 -38, 1.5 x 10 -10, 1.5 x 10 -4 3, 7.5 x 10 -4, 8.6 x 10 -9, 5.5 x 10 - 5, 4.3 x 10 -23, 3.1 x 10 -7, 9.2 x 10 -3, 1.2 x 10 -3, 1.4 x 10 -5, 1.3 x 10 -5, 6.3 x 10 -4, 2.3 x 10 -12, 8.6 x 10 -65, 7.2 x 10 -41, 1.1 x 10 -10, 1.8 x 10 -49, 2.1 x 10 -25, 3.8 x 10 -4, 7.2 x 10 -35, 4.2 x 10 -20, 2.0 x 10 -4, 5.0 x 10 -35, 2.0 x 10 -50, 8.0 x 10 -23, 8.9 x 10 -4 3, 1.4 x 10 -52, 8.2 x 10 -42, 4.2 x 10 -29, 3.8 x 10 -21, 1.8 x 10 -31, 1.7 x 10 -47, 7.3 x 10 -8, 2.2 x 10 -34, 8.7 x 10 -31, 2.2 x 10 -45, 6.1 x 10 -8, 8.2 x 10 -6, 7.6 x 10 -40, 7.0 x 10 -14, 5.7 x 10 -10, 2.1 x 10 -25, 8.6 x 10 -32, 5.3 x 10 -5, 5.3 x 10 -1, 5.7 x 10 -1, 4.6 x 10 -1, 2.6 x 10 -1, 3.7 x 10 -1, 3.8 x 10 -1.
