Stacked Bar Plot from Scientific Research

Proportion of cellular subpopulations within mPB HSPCs from experiments in o ( n = 3). Data are shown as mean s.e.m. Samples edited in BCL11A , CCR5 and IL2RG were unified for statistical analysis using a Friedman test with Dunn’s multiple comparison on the most primitive compartments (CD34 + CD133 + and CD34 + CD133 + CD90 + ), as experiments were performed in parallel on the same mPB HSPC donors. Cas9 and BE4max showed a significant reduction in the proportion of primitive compartments compared to ABE8.20-m ( P = 0.016 and P < 0.0001, respectively).

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