Mean cell scores, z-scored across cell type, of the lysine metabolism factor per study and cell type. Bars indicate mean z score per column (bottom) and participant numbers per study (right). Two-sided P values between plasma cells and other cell types were calculated using Wilcoxon matched-pairs signed-rank tests. (B cells: statistic = 2,903, Cohen’s d = 0.77; CD4 + T cells: statistic = 2,385, Cohen’s d = 0.88; CD8 + T cells: statistic = 4,555, Cohen’s d = 0.70; dendritic cells: statistic = 3,152, Cohen’s d = 0.76; granulocytes: statistic = 516, Cohen’s d = 0.91; macrophages: statistic = 2,350, Cohen’s d = 0.86; mast cells: statistic = 5,348, Cohen’s d = 0.52; NK cells: statistic = 3,883, Cohen’s d = 0.70; regulatory T cells: statistic = 4,441, Cohen’s d = 0.61; T cells: statistic = 3,345, Cohen’s d = 0.56). The studies listed in a , b and d are from Salcher et al. 71 .
