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The variational inference formulation quantifies the intrinsic uncertainty of a velocity estimate by sampling from the posterior distribution and measuring variability around the mean velocity vector. This notion is contrasted by its extrinsic counterpart, which quantifies variation of velocity extrapolated cell states within a cell’s neighborhood defined by transcriptomic similarity. KNN, k -nearest neighbor.
#Illustration#Variational Inference#Velocity Estimate#Posterior Distribution#Velocity Vector#Extrinsic Variation#Cell State#Transcriptomic Similarity#KNN#K-Nearest Neighbor
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