Workflow from Scientific Research

Open access visualization of Workflow, Illustration, Light-inducible transcription activation module, dCas9, Transcription activation domains
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The top shows the light-inducible transcription activation module (SCPTS), based on a dCas9 fused to transcription activation domains, driving CasRx transcription in this case. A U6 promoter-driven CasRx guide RNA can be co-expressed. The middle shows PA-TetON system. The bottom shows PA-Cre–Lox.

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