Line Plot from Scientific Research

Effect of tau K18 P301L on the temperature-dependence of the association equilibrium of DNAJA2, measured by DLS experiments in refolding buffer (20 mM Hepes-KOH pH 7.6, 50 mM KCl, 5 mM MgCl 2 and 2 mM DTT). Volume against size distribution of 30 uM DNAJA2 recorded at 25 C (top panel) or after incubating the sample 1 h at 40 C (middle panel) in the absence (blue) or presence (dashed red) of 30 uM tau K18 P301L. The reversibility of the association reaction was analysed after an o/n incubation at 25 C (bottom panel). A sample containing 30 uM tau K18 (black) was also analysed under the same conditions.

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