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CSF pNfH concentrations are positively correlated with disease duration during the first 25 months of symptomatic disease (Pearson, two-tailed, r = 0.60, P = 0.006) and negatively correlated with disease duration after 25 months (Pearson, two-tailed, r = 0.66, P = 1.7 x 10 -5).
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