Line Plot from Scientific Research

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The percent of the top N genes by different feature selection metrics that are differentially expressed. Data set is Sc-seq from three cancerous cell lines sequenced by Drop-seq (with 2005 differential expressed genes identified from non-parametric testing for each cell line versus the remaining; Wilcox test, fasle discovery rate corrected p -value < 0.05 ). The greater ability of scEC-impute to a priori select differentially expressed genes is repeated across each benchmark data set, see Additional file 1 : Fig. S2. Note that the imputation step in scEC-impute assigns many genes a heterogeneity I ( g ) of zero, resulting in a low cut-off on total number of selectable genes
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