Scatter Plot from Scientific Research

Log-transformed SPR binding off- ( k off ) versus on-rates ( k on ) against NPNA3 peptide of mAbs with either high SHM (purple, 20 nucleotide mutations per clone, n = 55) or low SHM (orange, <20 nucleotide mutations per clone, n = 14) and with activity weaker (downward-pointing triangles), not different to (circles) or better than (upward-pointing triangle) AB-000317 (two-tailed, nonparametric log-rank). mAbs from a lineage reported to bind CSP with FabFab homotypic interactions are indicated (black circles, AB-000399 (refs. 41 , 42 ), AB-007159, AB-007160, AB-007161).

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