Functions of the secretome predicted by conserved domains. The conserved domains of secreted proteins were predicted by the Interpro database using InterProScan ( https://www.ebi.ac.uk/interpro/ ), and total predicted proteins within the genome were set as the control. Columns in purple and blue color represent the number of proteins of the indicated conserved domains accession (IPR accession) from the secretome (axis on the right side) and whole genome (axis on the left side), respectively; the scale on the secretome or genome axes represents 500 or 20 genes, respectively. The outer circle with heatmap blocks represents the ratio of secretome versus the predicted proteins of the whole genome in the indicated IPR accession. The blue boxes link to IPR accessions represent the high ratio of indicated conserved domains in the secretome (number in red color) versus the genome (number in black color).