Baseline and follow-up results in percentile relative to age-matched peers in sustained attention (lower scores for detection represent improvement). The y axis represents the percentile and the x axis the mean; the middle line represents the median, the whisker lines the interquartile range (IQR) and single dots participants with a score >1.5 IQR. LME models were used for each comparison with FDR correction applied for determination of significance. * P FDR < 0.05; ** P FDR < 0.01; *** P FDR < 0.001. See Table 3 for P values and for the specific test item(s) included in each construct. The n for each construct at baseline, post-MISTIC and 1-month time points, respectively: detection, reaction time and sustained attention: 24, 28, and 20; verbal memory and working memory: 29, 30 and 27; visuospatial memory, processing speed, cognitive inhibition, cognitive flexibility composite, phonemic fluency and semantic fluency: 30, 30 and 27; problem-solving: 27, 30 and 27.
