ATAC-seq tracks for selected genes in NK cells from Sub-Cs ( n = 8 samples; top, black) versus Opt-Cs ( n = 8 samples; bottom, yellow). Box plots comparing the gene-level accessibility score between the two groups. P values were determined by two-tailed Students t -test in b and g , a two-tailed Wilcoxon rank-sum test in the volcano plot and a one-tailed binomial test for motif enrichment analysis in f . q values were determined by two-tailed two-sample t -test with false discovery rate correction for multiple testing in e . Data are shown as the mean + s.e.m.