Heatmap from Scientific Research

All SNVs ( n = 41,318,716) grouped by their pan-cancer recurrence count (1-7 + ). Heatmap showing the relative contribution (color) of all mutational signatures (x-axis) to hotspot mutations of increasing recurrence (y-axis). Colors represent log 2 -fold change in mean signature posterior probability relative to singleton SNVs (recurrence 1). Several mutational signatures are enriched (red) in highly recurrent hotspots (recurrence 5, 6, 7 + ).

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