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Patients are included in multiple groups if they had more than one mutation; patients can have multiple mutations in the same exon. Groups under each of the categories (KIT exon 9, 11, 13/14 or 17/18) are not mutually exclusive, and patients may appear in more than one box. Bold indicates patients who were included in the analysis populations for the current manuscript. CNV, copy number variation; QC, quality control; R, ripretinib; S, sunitinib. a ctDNA detected only for SNV/INDEL; two patients had CNV-only mutations and were categorized as ctDNA not detected.

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