Circos plot displaying genomic regions with recurrent somatic copy number alterations in human, feline, and canine UC. Chromosomes are represented by the outer track. Data for human chromosome X was not available. The histogram (inner track) shows the frequencies of copy number gains (purple, blue, and green) and losses (orange, red, and yellow) in human, canine, and feline, respectively. Links between chromosomes show syntenic regions within recurrently amplified/deleted chromosomes (feline and canine) or chromosome arms (human). Red links represent deletions and purple links represent amplifications. Genes shown in orange and purple text are in syntenic regions in chromosomes or chromosome arms that were recurrently deleted or amplified, respectively, in all 3 species. Genes in red and blue text are genes that were focally amplified or deleted in 2 or more species. ARHGEF10 is the only gene focally deleted in all 3 species. Shown in black text are other genes of interest
