Heatmap from Scientific Research

Plots of Spearman’s correlation between negative control samples (N = 20 each) in human and mouse, showing genome-wide correlation and correlation within the C&R suspect list regions in hg38 and mm10 genomes. In both human and mouse, samples show dramatically increased correlation when considering only the suspect list regions. The mouse dataset (15) that does not correlate well with the rest can be explained by an unequal distribution of reads among the chromosomes, with high enrichment for chromosome 1.

DOI