Box-and-whisker plot showing Euclidean distance from PCA separated by sex. The lower and upper hinges of the box correspond to the first and third quartiles (the 25th and 75th percentiles); the line in the box indicates the median. The upper whisker extends from the hinge to the largest value no further than 1.5 x interquartile range (IQR) from the hinge and the lower whisker extends from the hinge to the smallest value at most 1.5 x IQR from the hinge ( n = 20, 11 males/9 females). Significance was calculated by a paired two-sided t -test. ** P < 0.01. GO, gene ontology; FDR, false discovery rate.
