Heatmap from Scientific Research

Citation
Heatmap of baseline RNA expression ( Z -scores) of TME-specific signatures for leukocytes (CD45), cytotoxic cells, T cells, CD8 T cells, exhausted CD8 T cells, CD4 T cells, T reg cells, B cells, NK cells, eosinophils, macrophages, mast cells and neutrophils. Patients ( x axis) were ordered on the basis of hierarchical clustering (upper dendrogram). The squares below indicate Lauren classification, EBV status, MMR status, TMB (log 10 scale) and pathologic response per patient. The association of signature expression with response is shown on the right as a lollipop plot of signed, two-sided Wilcoxon rank-sum test-based P values (unadjusted for multiple hypothesis testing; x axis on log 10 scale).
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