Negative logarithm (base 10) of the p -value (-log10(pvalue) ) of hypergeometric tests of Gene Ontology (GO) term enrichments in the top 200 differentially expressed genes (DEGs) from bulk samples (72 affected vs 48 non-affected, Bulk), bootstrapped bulk profiles derived from the single cell data (100 affected vs 100 non-affected, BS-Bulk) and the cell type-specific bulk expression derived from BEDwARS deconvolution (72 affected vs 48 non-affected, CN-NEU, AS, CBC-INTER, PGC, BRC, NEC). None of the GO terms enriched in the top 200 DEGs of cell type-specific profiles are enriched in the top 200 DEGs derived from the bulk expression profiles. See Additional file 1 : Table S3 for information on GO terms.
