Mutational heatmap comparing patterns between the HOXA and HOXB groups. Colors represent mutation types, and molecular categories are annotated on the top. Bar plots on the right show frequencies of mutations in the HOXA and HOXB groups. Statistical significance of GRIN analysis in the HOXA and HOXB groups (*FDR < 0.05) and two-sided Fisher’s exact test between HOXA and HOXB groups (* P < 0.05, ** q < 0.05 after Benjamini–Hochberg adjustment) are also shown. GRIN results for FLT3 are for the entire gene, whereas Fisher’s tests were performed separately for ITD, TKD and non-TKD mutations.
