Many of the documents included data for more than one outcome indicator, so numbers shown for each indicator do not add to the total number of documents included in the systematic review. IDU=injecting drug use. IMEMR=Index Medicus for the Eastern Mediterranean Region. NSPs=needle and syringe programmes. OAT=opioid agonist treatment. *Reasons for exclusion were no data for the nine outcomes of interest, containing data for countries outside the Eastern Mediterranean region, containing data pre-dating 2010, and recruiting only students. †Reasons for exclusion were no data for the nine outcomes of interest; prevalence of people who inject drugs measured in a population at high risk (eg, among people who use drugs); prevalence of people who inject drugs measured in a specific population (eg, students); prevalence of HIV, hepatitis C virus, or hepatitis B virus measured in a population of people who inject drugs at high risk (eg, people who inject drugs admitted to infectious disease ward); and subnational data for the percentage of HIV infections due to IDU. ‡69 documents were included in the meta-analysis for all characteristics. §61 documents were included in the meta-analysis. ¶43 documents were included in the meta-analysis. ||31 documents were included in the meta-analysis.