Workflow from Scientific Research
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Two scenarios that violate the assumptions of TWAS and lead to false-positive findings. X is a noncausal gene of the trait y. X is associated with the trait, shown as dashed arrows, because of the LD between its eQTL and nearby causal variants. Double-headed arrows represent LD between variants.
#Workflow#Flowchart#Illustration#TWAS#False-Positive Findings#Noncausal Gene#Trait#eQTL#Causal Variants#Linkage Disequilibrium
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