Time-matched images of early embryogenesis showing that injection of a human homologous coPARSE-lncRNA RP1-212P9.3 fragment and an RP1-212P9.3 fragment with the intact NONO-binding sites (RP1-212P9.3 re1) rescued the developmental defect of the corresponding zebrafish lncRNA homolog knockdown embryos. The epiboly edge is marked by red dotted lines, and the embryonic shield is indicated by red arrowheads. n = 3 biologically independent experiments. The number of embryos in each injection group is detailed in Methods. Scale bars, 100 μm.
