Protein Structure from Scientific Research

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Structural overview of HLA-DR1-S486-505Omicron (BA.1) aligned and overlaid on top of the HLA-DR1-S486-505Wuhan HU-1 structure. For both, the HLA-DR1 peptide binding groove is shown as a gray cartoon representation, with the S486-505Omicron (BA.1) peptide shown as sticks (C atoms, pink) and S486-505Wuhan HU-1 peptide shown as sticks (C atoms, aqua). Amino acid mutations contained within S486-505Omicron (BA.1) that differ between variants are highlighted by the pink residue labels (inset).
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