Heatmap from Scientific Research

A simplified workflow for lncHOME analysis of vertebrate lncRNAs. The phylogenetic tree shows the evolutionary descent of eight vertebrates, with the number of annotated lncRNAs in each species. The heatmap shows the Jaccard index of lncRNAs and protein-coding genes identified by sequence similarity across eight vertebrates (top). lncHOME defines coPARSE-lncRNAs by combining the alignment of homologous protein-coding genes and corresponding genomic anchors (bottom left) and analysis of similar motif distribution patterns (bottom right).

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