Line Plot from Scientific Research

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Tolerance landscape plot of the TMEM63B protein provided by the MetaDome web server (https://stuart.radboudumc.nl/metadome/). The tool identifies regions of low tolerance to missense variations based on the local non-synonymous over synonymous variants ratio from gnomAD.15 All variants in our cohort are contained in intolerant/highly intolerant regions (in red) of the landscape.
#Line Plot#Heatmap#Tolerance Landscape Plot#TMEM63B Protein#MetaDome Web Server#Missense Variations#gnomAD
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