Table Image from Scientific Research

Multiple sequence alignment shows the protein sequence of the human TMEM63B protein (NP_060896.1) and of its orthologs in five different vertebrate species (Pan troglodytes, Sus scrofa, Mus musculus, Gallus gallus, Danio rerio) with the mutated residues in bold. The details of the TMEM63B variants in the cohort are displayed above the alignments. The asterisk below the sequence indicates positions that have a single, fully conserved residue between all the input sequences, the colon indicates conservation between groups of strongly similar properties, and the period indicates conservation between groups of weakly similar properties.

DOI