Heatmap from Scientific Research

Space-time plots over the last minute before macropinocytic cups close. Both lip and basal closures are included. Cups deepen particularly in the last 10 s before closure, as shown by the increasingly negative distance from the boundary. There is evidence for increased accumulation of PIP3 (n = 21) and F-actin (n = 16) at 10–40 s before closure. All data were obtained using Ax2 cells expressing a PIP3 reporter paired with the reporter of interest. All error bars represent standard error. Example images of each reporter are shown inFigure S3.

DOI