Bar Plot from Scientific Research

Cell-type specificity analysis was performed for GDM ( a ) and for prior meta-analysis of T2D ( b ) from ref. 18 using high-quality mouse single-cell RNA-seq datasets with FUMA v1.3.4 (Supplementary Tables 32 – 35 ). Unadjusted P values are reported for the two-sided association test between relative gene expression in the given cell type and multimarker analysis of genomic annotation (MAGMA) gene-level associations in the GWAS. Results are shown for cell types that both are significantly associated with at least one GWAS after correction for multiple testing of all cell types in all datasets ( a ) and have putatively independent association conditional on other cell types in the same RNA-seq dataset ( b ). Colors indicate the RNA-seq dataset source and significance.

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