A plot showing power-adjusted transferability (PAT) ratios. We first calculated the observed number of transferable loci out of the 195, 196, 179 and 180 loci that were present in the African, Hispanic/Latin American, South Asian and East Asian ancestries, respectively. These were divided by the expected number of transferable loci (numbers displayed underneath the figure), taking effect estimates from previous European ancestry studies, and allele frequency and sample size information from our African, Hispanic/Latin American, South Asian and East Asian ancestry cohorts. The ratios are presented separately for broadly defined MD and clinically ascertained MD. The error bars indicate 95% CIs for PAT ratios. We were unable to compute results for clinical MD in the Hispanic/Latin American group because of insufficient numbers of cases.
