Protein Structure from Scientific Research

TTC5 binds to the ribosome near the exit tunnel to capture the tubulin nascent chain (NC, red). The adaptor SCAPER is recruited via interactions with both TTC5 and the ribosome (PDB:8BPO). Only the C-terminal domain (CTD) of SCAPER is shown in this structure; the region that recruits the CCR4-NOT complex is part of an extended helix that was not visualized.

DOI