Bar Plot from Scientific Research

Significance (−log 10 ( P )) of Pearson’s r of orthologous gene effect size between pig ( n = 268) and human ( n = 136) traits derived from TWAS. Each bar represents a pig–human trait pair in the same tissue ( n = 11) and the within-domain blocks of color correspond to different human traits. The number of tested genes for each of the pairs is shown in Supplementary Table 30 . The text in the middle of the circle represents the significant examples of pig–human trait pairs in different thresholds. For each example, it includes human trait (top), pig trait (bottom) and TWAS tissue (left). P cutoff 1 : FDR < 10% across all tested combinations. P cutoff 2 : Bonferroni-corrected P < 5% within each trait–tissue pair of humans.

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