Protein Structure from Scientific Research

MD simulation reveals PI(4,5)P2 molecule (orange sticks) bound to the N terminus (binding site 1), and further three PI(4,5)P2 binding sites are shown (sites 2–4). SPNS2 is shown in blue (with the N terminus colored in yellow), the potential PI(4,5)P2 interacting residues are shown as blue sticks, and phosphorus atoms in the headgroups of membrane lipids are shown as gray spheres.

DOI