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NCI-H1975 monoclonalTMEM106BKOcells transduced with wild-type (WT) or mutantTMEM106BcDNA, infected with SARS-CoV-2 Belgium/GHB-03021/2020 or HCoV-229E. Cells were stained for dsRNA after 24 h (n = 12 wells from three experiments). Data were log-transformed and analyzed using one-way ANOVA with Dunnett’s multiple comparison test, comparing each condition with WT TMEM106B.
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