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The percentage of pachytene spermatocytes with or without synaptic defects in WT and Redic1 KI mice. The cells were divided into four groups: with fully synapsed chromosomes; with synapsis defects only on autosomes; with synapsis defects only on XY chromosomes; and with synapsis defects on both autosomes and XY chromosomes. The experiments were performed twice on two animals for each genotype. For WT mice, 169 pachytene spermatocytes were analyzed totally; for KI mice, 196 pachytene cells were analyzed totally. The bars indicate mean ± SD. ns, not significant ( P > 0.05); *** P < 0.001; two-way ANOVA. Redic1 KI mice represent mice carrying the homozygous mutation c.232_233insTT in Redic1 .
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