Microscopy from Scientific Research

CLEM of C2C12 cells expressing GFP-IRS-1 or GFP-IRS-1 2YA mutant. Scale bar, 0.4 m. Red asterisks (*) indicate nonmembrane GFP-IRS-1 foci while yellow arrows indicate ER. Minimum distance of ER located from the considered IRS-1 foci was quantified. Data are represented as mean ± SD. *** P < 0.001.

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