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Schematic model for the Trim37-mediated ubiquitination of Bcl6 and regulation of T FH cell differentiation. Data are representative of two ( e , f ) or at least three ( a d ) independent experiments, and were analyzed by two-tailed paired Student’s t -test ( e , f ). Data are mean SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, not significant.

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